Infant Formula Shortage

Updated 05/24/2022

Managing the Infant Formula Shortage

This is a difficult problem. Other than breast milk, there is no great substitute for infant formula.

A few things to avoid:

  • Home-made formulas are not the answer and are not recommended (contamination risks are significant; how the ingredients work together and are absorbed into the body - this is why formula exists)
  • Using extra water when mixing is not the answer. Young infants can have serious - even dangerous issues (hyponatremia) - with getting extra water
  • Do not hoard formula. When you find supply, take a reasonable amount for your infant, and leave some for others. The best solution to this problem will involve us all thinking about all infants in need.

The American Academy of Pediatrics has practical advice about what you can do about the formula shortage at its Healthy Children website.

Equivalent Formulas

The North Carolina Pediatric Society shared this chart with our office (their sources are listed below).

This chart groups together on the same rows different formulas that are basically very similar.

In general, you may substitute your child's formula with another formula listed on the same row. If you have a formula that is not on the same row as your child's formula, you may still be able to use it. Give us a call to find out.

Abbot Laboratories
Mead Johnson
Similac Brand
Enfamil Brand
Gerber Brand
Store Brands
Nutricia Brand
Similac 360 Total Care, Similac Pro-Advance, Similac Advance
Enfamil NeuroPro Infant, Enfamil Enspire, Enfamil Infant
Good Start, GentlePro
Parents Choice Advantage or Infant, Up&Up Advantage, Member's Mark Advantage, Mama Bear Advantage, Little Journey Advantage, CVS Advantage, Well Beginnings Advantage, Comforts (Kroger), Kirkland Signature ProCare

Standard Organic
Similac Organic
Enfamil Simply Organic

Earth's Best Organic

Mild Digestive Issues
Similac 360 Total Care Sensitive, Similac Pro-Sensitive,  Similac Sensitive
Enfamil NeuroPro Gentlease, Enfamil NeuroPro Sensitive
Good Start, SoothePro
Parent’s Choice Sensitivity, Up&Up Sensitivity, Member’s Mark Sensitivity, Mama Bear Sensitivity, Little Journey Sensitivity, CVS Sensitivity

Similac Pro-Total Comfort, Similac Total Comfort
Enfamil NeuroPro Gentlease, Enfamil Gentlease
Good Start, SoothePro
Parent’s Choice Complete Comfort, Up&Up Complete Comfort, CVS Complete Comfort

Enfamil Reguline

Burt’s Bees Baby Ultra Gentle Organic, Parent’s Choice Tender

Similac For Spit Up
Enfamil AR
Good Start, Gentle Supreme
Parent’s Choice Added Rice Starch, Up&Up Added Rice Starch

Similac Soy Isomil
Enfamil Prosobee
Gentle Soy
Parent’s Choice Soy, Up&Up Soy, Comforts Soy (Kroger)

Similac Alimentum
Nutramigen or Pregestimil
Extensive HA
Parent's Choice Hypoallergenic, Up&Up Hypoallergenic, CVS Health Hypoallergenic, Mama Bear Hypoallergenic


Neocate Infant, Neocate Syneo

EleCare Unflavored
PurAmino Jr Unflavored
Alfamino Jr

Neocate Jr, Neocate Splash
Similac Neosure - 22 Cal
Enfamil NeuroPro EnfaCare - 22 Cal

Similac Special Care - 20 Cal
Enfamil Premature - 20 Cal

Similac Special Care - 24 CalEnfamil Premature - 24 Cal

Similac Special Care High Protein - 24 CalEnfamil Premature High Protein - 24 Cal

Similac Special Care - 30 CalEnfamil Premature - 30 Cal

Special Dietary Needs
Ketonex-1BCAD 1

Ketonex-2BCAD 2

Glutarex-1 or Glutarex-2

Hominix-1HCY 1

Hominix-2HCY 2

I-Valex-1 or I-Valex-2

Propimex-1OA 1

Propimex-2OA 2

Phenex-1Phenyl-Free 1

Phenex-2Phenyl-Free 2

Phenyl-Free HP

Pro-PhreePFD Toddler


Tyrex-1TYROS 1

Tyrex-2TYROS 2

Cyclinex-1WND 1

Cyclinex-2WND 2



Store Brands: Parent’s Choice – Walmart, Member’s Mark – Sam’s Club, Up&Up – Target, Comforts – Kroger, Kirkland – Costco, Mama Bear – Amazon, Little Journey – Aldo, Well beginnings - Walgreens

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Raleigh, NC. 27612


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Raleigh, NC. 27617


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